Gregor Townsend has made six changes to his Scotland side to face England in the final Six Nations fixture on Saturday.

Injuries to key players have knocked the Scots' campaign off-course and Townsend is looking to get his side back on track in a bid to defend the Calcutta Cup.

Jonny Gray has been dropped to the bench as Scotland look to find a winning formula after three straight losses, with Edinburgh's Ben Toolis replacing the Glasgow star.

With Blair Kinghorn and Tommy Seymour sidelined, Saracens' Sean Maitland and Sale Sharks' Bryan McGuigan step into the back-three.

Warriors inside-centre Sam Johnson takes club-mate Peter Horne's spot.

Hamish Watson, the Edinburgh openside, starts in the back-row instead of Jamie Ritchie, who missed out with a neck injury sustained in the loss to Wales.

Exeter Chiefs forward Sam Skinner returns after missing out since the opening win over Italy.

England's Grand Slam bid was wrecked by defeat to Wales but they can still claim the title if Warren Gatland's side slip up at home to Ireland.

Townsend said: "England are a quality side and have been playing really well throughout the championship.

"They have shown a different game plan this season which is built on power, both through direct ball carrying and also getting off the line in defence.

"They've kicked the ball more than any other team in the Guinness Six Nations, which has worked well for them and produced tries, and it also shows that they are more than comfortable defending for several phases."