Watch highlights of the week's Europa League last 32 action
Man Utd faced Midtylland, Liverpool were up against Augsburg and Spurs had Fiorentina.
Missed Thursday's night round of 32 action in the Europa League? Watch highlights of every game here.
Manchester United eventually handed out a 5-1 thumping to FC Midtylland but not after the Danish side had given Louis Van Gaal and his Red Devils a scare.
Liverpool edged past Augsburg in a nervy tie at Anfield, with Tottenham securing their place in the last 16 with a 3-0 win over Italian Serie A outfit Fiorentina at White Hart Lane.
Porto faced Borussia Dortmund, whilst Molde hosted reigning champions Sevilla and Napoli were paired against Villarreal.
Watch highlights of the last 32 action in the Europa League below.
Manchester United progressed into the last 16 of the competition with an ultimately impressive 5-1 win over FC Midtylland, although they were made to work for the victory.
The Danish side took the lead but a double from debutant Marcus Rashford helped the Red Devills into the next round of the Europa League.
James Milner scored an early penalty kick for Jurgen Klopp's Liverpool side as they edged past Augsburg.
The Bundesliga side made a fight of the contest, though, with the Reds somewhat holding on for the nervy win towards the end.
Elsewhere, Porto claimed a 1-0 win over Borussia Dortmund, Napoli drew 1-1 with Villarreal and Basel beat St Etienne 2-1 in Switzerland. Meanwhile Anderlecht secured a 2-1 win over Olympiakos.
Molde beat Sevilla 1-0, but still went out on aggregate, whilst Lazio claimed a 3-1 win over Galatasaray. Bayer Leverkusen scored a couple of stunning strikes in a 3-1 victory against Sporting Lisbon, and Shakhtar Donetsk also scored three themselves in an impressive win over Schalke.
There was a 1-1 draw between Lokomotiv Moscow and Fenerbahce. Sparta Prague inflicted a 3-0 defeat on Krasnodar, with Athletic Bilbao and Marseille drawing 1-1 at San Mames. Sporting Braga and Sion also drew, but there was a comprehensive 4-0 win for Gary Neville's Valencia against Rapid Vienna.