Taxi firm Uber's licence has been revoked in London
Transport for London has revoked the company's right to operate in the UK capital.
Uber's operating licence in the UK capital has been revoked, Transport for London (TfL) has announced.
It comes after months of debate over passenger safety and vetting of drivers.
Withdrawing the licence, TfL described Uber as not being "fit and proper" to offer its services to Londoners.
Mayor Sadiq Khan said the decision had been made to protect customer safety, adding that all companies must "play by the rules".
The company criticised the decision, saying that "far from being open, London is closed to innovative companies".
Uber's London licence will expire on September 30.
The company can continue to operate beyond the expiry date, however, if it decides to appeal the decision.
The decision is likely to be welcomed by Uber's growing critics, who argue the company has exacerbated London's traffic congestion and done little to address incidents of violence involving its drivers.
Labour MP Wes Streeting, chairman of the All Party Parliamentary Group, described the decision as "courageous".
"Uber has not shown itself to be a fit and proper operator," he said.
"It stands accused by the police of failing to properly handle serious allegations of rape and sexual assault of passengers.
"It had to be dragged through the courts to recognise its responsibility to provide even the most basic rights and protections to Uber drivers.
"Its business model is based on saturating London's taxi and private hire market to drive its competition off the road."
Meanwhile, Steve McNamara, general secretary of the Licensed Taxi Drivers' Association said TfL had made the "right call".
"Since it first came onto our streets Uber has broken the law, exploited its drivers and refused to take responsibility for the safety of passengers," he said.
"We expect Uber will again embark on a spurious legal challenge against the Mayor and TfL, and we will urge the court to uphold this decision."
There had been growing speculation that the app could be banned from London.
Opponents of the firm claim it causes gridlocked roads and does not do enough to regulate its drivers.
Uber enables users to book cars using their smartphones, and is available in cities across the UK.
Some 3.5 million passengers and 40,000 drivers use the Uber app in London.