The parents of sick Charlie Gard have lost their Supreme Court fight to take their son to America for treatment.

Chris Gard and Connie Yates want the ten-month-old, who suffers from a rare genetic condition and has brain damage, to undergo a therapy trial.

Charlie's mother broke down in tears and screamed as justices announced their decision and was led from the court by lawyers.

Specialists at Great Ormond Street Hospital in London, where Charlie is being cared for, say therapy proposed by a doctor in America is experimental and will not help.

They say life support treatment should stop.

A High Court judge in April ruled against a trip to America and in favour of Great Ormond Street doctors.

Mr Justice Francis concluded that life support treatment should end and said Charlie should be allowed to die with dignity.

Three Court of Appeal judges upheld that ruling in May.

A panel of three Supreme Court justices on Thursday dismissed the couple's latest challenge after a hearing in London.

The Supreme Court justices said doctors should continue life support treatment for Charlie for 24 hours to give the European Court of Human Rights the chance to consider the case.