This is the moment that a woman targeted by burglars leaped out of bed and opened fire on the intruders.

One was shot dead by the female business owner during the late-night confrontation in Gwinnett County in the US state of Georgia.

Security video captured the burglars as they stopped ransacking the house and suddenly turned tail and fled after the householder opened fire.

The woman is seen chasing them out of the door while continuing to fire her gun, before calming turning and walking back into the house.

Police said the householder was a businesswoman who was thought to have been deliberately targeted by the burglars.

She woke up after her door was kicked in by the three men and opened fire on the intruders.

One man was fatally shot in the chest and died despite CPR efforts at the scene.

His two accomplices are still being sought and are being considered "armed and dangerous" by officers.

Police said they did not expect to bring charges against the female householder who opened fire on the burglars.